In the earlier 1990's, the United States' diet craze and mission for thinness found a new drug of choice, Fen-Phen, guaranteed to help users finally lose weight. Two drugs, fenfluramine and phentermine, came up with the Fen-Phen cocktail. Fenfluramine works in the body by releasing extra amounts of serotonin, which is the neurotransmitter in charge of feelings of satiety and fullness. Phentermine, a stimulant, would counteract the drowsiness inducing qualities of a surge of appetite reducing hormones. The two drugs had fewer side effects when taken together than when taken individually. Despite the fact that America had not recently been diet drug crazy since the amphetamine use of the 1960's, Fen-Phen appeared like a different sort of weight loss aid. A 1983 study over the course of four years found that obese patients (those weighing 200 pounds or more) lost 32 pounds on average when taking the drug drink. This research, together with the medical community's support and users' results, allowed Fen-Phen to dominate the diet medication market in the 1990's.
In 1996 alone, there was 18 million prescriptions written for Fen-Phen. American Residence Products, the company accountable for manufacturing Fen-Phen, made Fen-Phen available to the public without proper warnings and phenq part effect information. In April 1996, American Home Goods also started out producing Redux, a diet drug that was approved to sell despite a 5-3 election by a scientific screen against its approval. Within a year and a half after its approval, 2. 5 million prescriptions for Redux had already recently been written for dieters.
In 1997, the Mayo Clinic released a study concerning the serious side effects and everlasting health problems resulting from the utilization of Fen-Phen. The most common side-effect of the drug was heart valve defects, more specifically aortic and mitral valves. The heart problems triggered by Fen-Phen would require risky heart surgery. Additional difficulties included primary pulmonary hypertension, a devastating disease in which blood pressure in the pulmonary artery goes up to dangerous levels and creates additional cardiac stress. Soon after, in September 1997, the Food and Drug Administration (FDA) pulled the diet drugs from the market. With this point, Us Home Products had made about $200 million from cashing in on the diet program craze.